Document Detail


Possible interaction between pomegranate juice and warfarin.
MedLine Citation:
PMID:  20029019     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Pomegranate juice is growing in popularity in the UK. We report a potential interaction between pomegranate juice and warfarin. Laboratory studies have shown that pomegranate juice inhibits cytochrome P450 enzymes involved in warfarin metabolism. As with previous reports of interactions between food and warfarin, this case does not definitively prove the association between pomegranate juice consumption and increased warfarin bioactivity but highlights the importance of taking a complete drug, food and juice history when assessing patients with unstable anticoagulation.
Authors:
S Jarvis; C Li; R G Bogle
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Emergency medicine journal : EMJ     Volume:  27     ISSN:  1472-0213     ISO Abbreviation:  Emerg Med J     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2009-12-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100963089     Medline TA:  Emerg Med J     Country:  England    
Other Details:
Languages:  eng     Pagination:  74-5     Citation Subset:  IM    
Affiliation:
Imperial Healthcare NHS Trust, Hammersmith Campus, DuCane Road, London W12 0NN, UK. sheba.jarvis@imperial.ac.uk
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