Document Detail


Possible gender differences in the effect of exercise on hypoxic ventilatory response.
MedLine Citation:
PMID:  3138747     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Gender differences in resting ventilation and hypoxic ventilatory response (HVR) have been reported. Ventilation and HVR are closely related to changes in metabolic rate in men. However, it is unclear whether there is a comparable relationship between metabolic rate and ventilation or HVR in women. We studied 13 men and 12 women to determine whether exercise-induced increases in metabolic rate influenced ventilation, HVR, and hypercapnic ventilatory response (HCVR) differently in men and women. Minute ventilation per unit metabolic rate was higher (lower end-tidal PCO2) in women than men during rest and mild exercise. Resting HVR values were similar in men and women. With mild, exercise-induced increases in O2 consumption (24 +/- 4% in men and 27 +/- 2% in women, p = NS), HVR increased in men (p less than 0.05) but not in women. Moderate exercise-induced increases in O2 consumption (313 +/- 13% in men and 330 +/- 13% in women, p = NS), raised hypoxic responses in both sexes. HCVR values were similar in men and women at rest and during mild exercise. Moderate exercise increased HCVR equally in the sexes. Thus the higher resting ventilation and lesser change in HVR during mild exercise suggested that women were less sensitive to mild metabolic rate stimulation than men.
Authors:
J G Regensteiner; C K Pickett; R E McCullough; J V Weil; L G Moore
Related Documents :
12761007 - An evaluation of the laryngeal tube during general anesthesia using mechanical ventilat...
1152087 - Ventilatory patterns following burn injury and effect of sulfamylon.
15676377 - Circulo-respiratory efficiency in some agricultural work.
11175247 - Monitoring and humidification during tracheal gas insufflation.
9432407 - Cardiovascular and respiratory adjustments in normal volunteers during modified exercis...
19466447 - Antioxidant and redox status after maximal aerobic exercise at high altitude in acclima...
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Respiration; international review of thoracic diseases     Volume:  53     ISSN:  0025-7931     ISO Abbreviation:  Respiration     Publication Date:  1988  
Date Detail:
Created Date:  1988-10-18     Completed Date:  1988-10-18     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0137356     Medline TA:  Respiration     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  158-65     Citation Subset:  IM; S    
Affiliation:
Cardiovascular Pulmonary Research Laboratory, University of Colorado, Denver.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Anoxia / metabolism,  physiopathology*
Carbon Dioxide
Female
Humans
Hypercapnia / physiopathology
Male
Oxygen
Oxygen Consumption
Partial Pressure
Physical Exertion*
Respiration*
Sex Characteristics*
Tidal Volume
Grant Support
ID/Acronym/Agency:
HD 00981/HD/NICHD NIH HHS; HL 14985/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
124-38-9/Carbon Dioxide; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Cardiorespiratory function and pathological findings in heart-lung block reimplanted after hypotherm...
Next Document:  Absence of CO2-sensitive venous chemoreceptors in the cat.