| Possible gender differences in the effect of exercise on hypoxic ventilatory response. | |
| | |
MedLine Citation:
|
PMID: 3138747 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Gender differences in resting ventilation and hypoxic ventilatory response (HVR) have been reported. Ventilation and HVR are closely related to changes in metabolic rate in men. However, it is unclear whether there is a comparable relationship between metabolic rate and ventilation or HVR in women. We studied 13 men and 12 women to determine whether exercise-induced increases in metabolic rate influenced ventilation, HVR, and hypercapnic ventilatory response (HCVR) differently in men and women. Minute ventilation per unit metabolic rate was higher (lower end-tidal PCO2) in women than men during rest and mild exercise. Resting HVR values were similar in men and women. With mild, exercise-induced increases in O2 consumption (24 +/- 4% in men and 27 +/- 2% in women, p = NS), HVR increased in men (p less than 0.05) but not in women. Moderate exercise-induced increases in O2 consumption (313 +/- 13% in men and 330 +/- 13% in women, p = NS), raised hypoxic responses in both sexes. HCVR values were similar in men and women at rest and during mild exercise. Moderate exercise increased HCVR equally in the sexes. Thus the higher resting ventilation and lesser change in HVR during mild exercise suggested that women were less sensitive to mild metabolic rate stimulation than men. |
| | |
Authors:
|
J G Regensteiner; C K Pickett; R E McCullough; J V Weil; L G Moore |
Related Documents
:
|
12761007 - An evaluation of the laryngeal tube during general anesthesia using mechanical ventilat... 1152087 - Ventilatory patterns following burn injury and effect of sulfamylon. 15676377 - Circulo-respiratory efficiency in some agricultural work. 11175247 - Monitoring and humidification during tracheal gas insufflation. 9432407 - Cardiovascular and respiratory adjustments in normal volunteers during modified exercis... 19466447 - Antioxidant and redox status after maximal aerobic exercise at high altitude in acclima... |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Respiration; international review of thoracic diseases Volume: 53 ISSN: 0025-7931 ISO Abbreviation: Respiration Publication Date: 1988 |
Date Detail:
|
Created Date: 1988-10-18 Completed Date: 1988-10-18 Revised Date: 2009-11-11 |
Medline Journal Info:
|
Nlm Unique ID: 0137356 Medline TA: Respiration Country: SWITZERLAND |
Other Details:
|
Languages: eng Pagination: 158-65 Citation Subset: IM; S |
Affiliation:
|
Cardiovascular Pulmonary Research Laboratory, University of Colorado, Denver. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Anoxia / metabolism, physiopathology* Carbon Dioxide Female Humans Hypercapnia / physiopathology Male Oxygen Oxygen Consumption Partial Pressure Physical Exertion* Respiration* Sex Characteristics* Tidal Volume |
| Grant Support | |
ID/Acronym/Agency:
|
HD 00981/HD/NICHD NIH HHS; HL 14985/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
|
124-38-9/Carbon Dioxide; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Cardiorespiratory function and pathological findings in heart-lung block reimplanted after hypotherm...
Next Document: Absence of CO2-sensitive venous chemoreceptors in the cat.