Document Detail


Possible association of oncornavirus type D with some forms of human cancer.
MedLine Citation:
PMID:  50567     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The method of molecular hybridization of nucleic acids of oncornavirus type D produced by HEp2 cells with cellular nucleic acids was applied. No sequences homologous to the viral nucleic acids were found in normal human embryo cells as well as in bovine, porcine, murine, and chicken cells. No such sequences were found in tissues of malignant lymphomas. Sequences homologous to the viral nucleic acids were found in some cancer cells, predominantly in hormone-associated tumors of females.
Authors:
V M Zhdanov; G N Trushinskaya; N N Mazurenko; G K Zairov
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neoplasma     Volume:  22     ISSN:  0028-2685     ISO Abbreviation:  Neoplasma     Publication Date:  1975  
Date Detail:
Created Date:  1975-11-07     Completed Date:  1975-11-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0377266     Medline TA:  Neoplasma     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  13-21     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Breast Neoplasms / enzymology
Cattle
Chick Embryo
DNA Nucleotidyltransferases / metabolism
DNA, Viral / metabolism
Female
Humans
Lymphoma / metabolism*
Mice
Nucleic Acid Hybridization
Oncogenic Viruses / metabolism,  physiology*
Ovarian Neoplasms / enzymology
RNA, Viral / metabolism
RNA-Directed DNA Polymerase / metabolism
Stomach Neoplasms / enzymology
Swine
Virus Cultivation
Virus Replication
Chemical
Reg. No./Substance:
0/DNA, Viral; 0/RNA, Viral; EC 2.7.7.-/DNA Nucleotidyltransferases; EC 2.7.7.49/RNA-Directed DNA Polymerase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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