| Possible association of influenza A with fetal loss: investigation of a cluster of spontaneous abortions and stillbirths. | |
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MedLine Citation:
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PMID: 7513232 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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It has been suspected that influenza infection is associated with fetal or perinatal mortality, but little recent evidence supports this hypothesis. A small cluster of early and late fetal deaths in early 1986 prompted an epidemiological investigation. Women whose pregnancies were affected (cases) were compared with women whose pregnancies had a normal outcome (controls). Case pregnancies were distinguished by a significant excess of recent flu-like illness (p = 0.006), and were significantly more likely than controls to have serological evidence of influenza A infection (p = 0.00067), predominantly the influenza A H3N2, Christchurch/4/85-like strain. The cluster was recognised because most cases were patients of one health centre. Larger epidemiological studies will be needed to confirm an association between influenza A and fetal death, but this cluster suggests that influenza A may have an adverse influence on fetal survival. |
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Authors:
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R Stanwell-Smith; A M Parker; P Chakraverty; N Soltanpoor; C N Simpson |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Communicable disease report. CDR review Volume: 4 ISSN: 1350-9349 ISO Abbreviation: Commun Dis Rep CDR Rev Publication Date: 1994 Mar |
Date Detail:
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Created Date: 1994-06-02 Completed Date: 1994-06-02 Revised Date: 2005-11-22 |
Medline Journal Info:
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Nlm Unique ID: 9312372 Medline TA: Commun Dis Rep CDR Rev Country: ENGLAND |
Other Details:
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Languages: eng Pagination: R28-32 Citation Subset: IM |
Affiliation:
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PHLS Communicable Disease Surveillance Centre, London. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Spontaneous
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etiology* Adult Cluster Analysis England / epidemiology Female Fetal Death / etiology* Humans Influenza A virus* Influenza, Human / complications*, epidemiology Pregnancy Pregnancy Complications, Infectious* / epidemiology Wales / epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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