Document Detail


Possible andrologic markers in elevated neonatal 17-hydroxyprogesterone.
MedLine Citation:
PMID:  20537623     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this prospective study, we analyzed 30 male infants with increased neonatal 17-hydroxyprogesterone (17OH-P) (patients) and for comparison 52 age-matched healthy babies (control subjects) with the aim of investigating the hypothalamic-pituitary-testis axis in the first 6 months of life. Although T, FSH, and LH levels were not significantly different in patients and control subjects, inhibin B was higher in patients than in control subjects. Therefore we suggest a clinical follow-up of these babies during childhood and puberty to verify the evolution of their condition.
Authors:
Paolo Cavarzere; Monica Vincenzi; Rossella Gaudino; Roberto Franceschi; Silvia Perlini; Marta Camilot; Francesca Teofoli; Franco Antoniazzi; Luciano Tatò
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Publication Detail:
Type:  Evaluation Studies; Journal Article     Date:  2010-05-26
Journal Detail:
Title:  Fertility and sterility     Volume:  94     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-27     Completed Date:  2010-12-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2350-2     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Affiliation:
Pediatric Clinic, Department of Mother and Child, University of Verona, Verona, Italy. paolocavarzere@yahoo.it
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MeSH Terms
Descriptor/Qualifier:
17-alpha-Hydroxyprogesterone / blood*,  metabolism
Adrenal Hyperplasia, Congenital / blood*,  diagnosis*,  metabolism
Andrology / methods
Biological Markers / analysis*,  blood
Case-Control Studies
Follow-Up Studies
Humans
Infant, Newborn / blood*
Male
Neonatal Screening / methods
Steroid 21-Hydroxylase / metabolism
Up-Regulation
Chemical
Reg. No./Substance:
0/Biological Markers; 68-96-2/17-alpha-Hydroxyprogesterone; EC 1.14.99.10/Steroid 21-Hydroxylase

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