| Possible andrologic markers in elevated neonatal 17-hydroxyprogesterone. | |
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MedLine Citation:
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PMID: 20537623 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In this prospective study, we analyzed 30 male infants with increased neonatal 17-hydroxyprogesterone (17OH-P) (patients) and for comparison 52 age-matched healthy babies (control subjects) with the aim of investigating the hypothalamic-pituitary-testis axis in the first 6 months of life. Although T, FSH, and LH levels were not significantly different in patients and control subjects, inhibin B was higher in patients than in control subjects. Therefore we suggest a clinical follow-up of these babies during childhood and puberty to verify the evolution of their condition. |
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Authors:
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Paolo Cavarzere; Monica Vincenzi; Rossella Gaudino; Roberto Franceschi; Silvia Perlini; Marta Camilot; Francesca Teofoli; Franco Antoniazzi; Luciano Tatò |
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Publication Detail:
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Type: Evaluation Studies; Journal Article Date: 2010-05-26 |
Journal Detail:
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Title: Fertility and sterility Volume: 94 ISSN: 1556-5653 ISO Abbreviation: Fertil. Steril. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-27 Completed Date: 2010-12-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 2350-2 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Pediatric Clinic, Department of Mother and Child, University of Verona, Verona, Italy. paolocavarzere@yahoo.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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17-alpha-Hydroxyprogesterone
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blood*,
metabolism Adrenal Hyperplasia, Congenital / blood*, diagnosis*, metabolism Andrology / methods Biological Markers / analysis*, blood Case-Control Studies Follow-Up Studies Humans Infant, Newborn / blood* Male Neonatal Screening / methods Steroid 21-Hydroxylase / metabolism Up-Regulation |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 68-96-2/17-alpha-Hydroxyprogesterone; EC 1.14.99.10/Steroid 21-Hydroxylase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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