| Possibility of influencing drug release from polymers--using the example of bead polymers | |
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MedLine Citation:
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PMID: 6669615 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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By the example of the model drug phenobarbital, the authors report of the possibilities of influencing the liberation of drugs from acrylate-based bead polymers. The drug-containing bead polymers produced were studied in vitro (half-change method, beaker device according to Moldenhauer, artificial digestive juices according to Münzel, without addition of enzymes). The composition of a unit-dose preparation, composed of several batches prepared under different conditions, is dealt with. The release values obtained largely meet the requirements made on depot preparations. |
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Authors:
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R Mank; H Kala |
Publication Detail:
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Type: English Abstract; Journal Article |
Journal Detail:
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Title: Die Pharmazie Volume: 38 ISSN: 0031-7144 ISO Abbreviation: Pharmazie Publication Date: 1983 Dec |
Date Detail:
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Created Date: 1984-04-26 Completed Date: 1984-04-26 Revised Date: 2007-01-29 |
Medline Journal Info:
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Nlm Unique ID: 9800766 Medline TA: Pharmazie Country: GERMANY, EAST |
Other Details:
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Languages: ger Pagination: 860-4 Citation Subset: IM |
Vernacular Title:
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Möglichkeiten der Beeinflussung des Liberationsverhaltens von Arzneistoffen aus Polymeren-dargestellt am Beispiel von Perlpolymerisaten. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acrylic Resins Chemistry, Pharmaceutical Delayed-Action Preparations* Phenobarbital / administration & dosage Polymers Solubility Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Acrylic Resins; 0/Delayed-Action Preparations; 0/Polymers; 50-06-6/Phenobarbital |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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