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Possibilities and limitations in imaging the intracranial arteries in the context of a contrast-enhanced whole-body magnetic resonance angiographic screening protocol at 1.5 versus 3 tesla.
MedLine Citation:
PMID:  21150452     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
OBJECTIVE: : Evaluation of the diagnostic detectability of the intracranial vasculature on contrast-enhanced whole-body magnetic resonance angiographic (WBMRA) scans at 1.5 versus 3 T.
METHODS: : Twenty-seven patients with hereditary hyperlipidemia participated. Two experienced neuroradiologists scored the image quality regarding the intracranial arteries applying a 5-point scale. Stenoses and other findings were documented. Weighted κ-statistics were calculated to assess interobserver agreement.
RESULTS: : Interobserver agreement was very good. Image quality scoring resulted in the following mean values: 3.0 at 1.5 T versus 3.9 at 3 T (P < 0.001). Venous contrast overlay and insufficient anatomic coverage occurred in both groups. Three stenoses were found at both field strengths.
CONCLUSIONS: : Assessment of the intracranial vasculature on WBMRA data is basically feasible; image quality at 3 T seems superior. Shortcomings appear because of venous contamination and insufficient volume coverage. Therefore, adding a dedicated intracranial MRA to a WBMRA protocol would substantially increase diagnostic certainty.
Authors:
Jan-Hendrik Buhk; Thorsten Ries; Anna-Katharina Finck-Wedel; Frank Ulrich Beil; Gerhard Adam; Christoph Weber
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of computer assisted tomography     Volume:  35     ISSN:  1532-3145     ISO Abbreviation:  J Comput Assist Tomogr     Publication Date:    2011 Jan-Feb
Date Detail:
Created Date:  2011-01-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7703942     Medline TA:  J Comput Assist Tomogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  4-8     Citation Subset:  IM    
Affiliation:
From the Departments of *Diagnostic and Interventional Radiology, †Neuroradiology, and ‡Internal Medicine, Medical Clinic III, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
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