| Positron emission tomography within a magnetic field using photomultiplier tubes and lightguides. | |
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MedLine Citation:
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PMID: 7610123 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The spatial resolution of positron emission tomography (PET) improves when positron annihilation takes place in a strong magnetic field. In a magnetic field, the Lorentz force restricts positron range perpendicular to the field. Since positron annihilation occurs closer to its point of origin, the positron annihilation point spread function decreases. This was verified experimentally by measuring the spread function of positron annihilation from a 500 mm 68Ge bead imbedded in tissue-equivalent wax. At 5 T the spread function full width at half maximum (FWHM) and the full width at tenth maximum (FWTM) decrease by a factor of 1.42 and 2.09, respectively. Two NaI(Tl) scintillation crystals that interface to a pair of photomultiplier tubes (PMTS) through long lightguides detect positron annihilation at zero field and 5.0 T. Photomultiplier tubes, inoperable in strong magnetic fields, are functional if lightguides bring the photons produced by scintillators within the field to a minimal magnetic field. These tests also demonstrate techniques necessary for combining magnetic resonance imaging (MRI) and PET into one scanner. |
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Authors:
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N L Christensen; B E Hammer; B G Heil; K Fetterly |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Physics in medicine and biology Volume: 40 ISSN: 0031-9155 ISO Abbreviation: Phys Med Biol Publication Date: 1995 Apr |
Date Detail:
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Created Date: 1995-08-16 Completed Date: 1995-08-16 Revised Date: 2011-02-11 |
Medline Journal Info:
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Nlm Unique ID: 0401220 Medline TA: Phys Med Biol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 691-7 Citation Subset: IM |
Affiliation:
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School of Physics and Astronomy, University of Minnesota, Minneapolis 55455, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Gamma Rays Germanium Humans Magnetics* Radioisotopes Tomography, Emission-Computed / instrumentation*, methods |
| Grant Support | |
ID/Acronym/Agency:
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R29 CA065523-05/CA/NCI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Radioisotopes; 7440-56-4/Germanium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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