| Positron emission tomography/computer tomography: challenge to conventional imaging modalities in evaluating primary and metastatic liver malignancies. | |
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MedLine Citation:
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PMID: 17569111 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Computer tomography (CT) and magnetic resonance imaging (MRI), as conventional imaging modalities, are the preferred methodology for tumor, nodal and systemic metastasis (TNM) staging. However, all the noninvasive techniques in current use are not sufficiently able to identify primary tumors and even unable to define the extent of metastatic spread. In addition, relying exclusively on macromorphological characteristics to make a conclusion runs the risk of misdiagnosis due mainly to the intrinsic limitations of the imaging modalities themselves. Solely based on the macromorphological characteristics of cancer, one cannot give an appropriate assessment of the biological characteristics of tumors. Currently, positron emission tomography/computer tomography (PET/CT) are more and more widely available and their application with (18)F-fluorodeoxyglucose ((18)F-FDG) in oncology has become one of the standard imaging modalities in diagnosing and staging of tumors, and monitoring the therapeutic efficacy in hepatic malignancies. Recently, investigators have measured glucose utilization in liver tumors using (18)F-FDG, PET and PET/CT in order to establish diagnosis of tumors, assess their biologic characteristics and predict therapeutic effects on hepatic malignancies. PET/CT with (18)F-FDG as a radiotracer may further enhance the hepatic malignancy diagnostic algorithm by accurate diagnosis, staging, restaging and evaluating its biological characteristics, which can benefit the patients suffering from hepatic metastases, hepatocellular carcinoma and cholangiocarcinoma. |
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Authors:
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Long Sun; Hua Wu; Yong-Song Guan |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: World journal of gastroenterology : WJG Volume: 13 ISSN: 1007-9327 ISO Abbreviation: World J. Gastroenterol. Publication Date: 2007 May |
Date Detail:
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Created Date: 2007-06-14 Completed Date: 2007-08-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100883448 Medline TA: World J Gastroenterol Country: China |
Other Details:
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Languages: eng Pagination: 2775-83 Citation Subset: IM |
Affiliation:
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Minnan PET Center, The First Hospital of Xiamen, Fujian Medical University, Xiamen, China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Algorithms Humans Liver Neoplasms / radiography*, radionuclide imaging*, secondary Neoplasm Metastasis / radiography, radionuclide imaging Neoplasm Recurrence, Local / radiography, radionuclide imaging Neoplasm Staging Positron-Emission Tomography / methods* Prognosis Tomography, X-Ray Computed / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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