Document Detail

Positron emission tomography for the assessment of myocardial viability in Kawasaki disease using different therapies.
MedLine Citation:
PMID:  10994666     Owner:  NLM     Status:  MEDLINE    
13N-ammonia and 18F-fluorodeoxyglucose positron emission tomography (PET) of the heart were performed on 30 children with a history of Kawasaki disease. The results indicated PET abnormalities in 61.1% of patients during the acute and subacute stages and in 41.2% of patients in the convalescent stage of Kawasaki disease. Two-dimensional echocardiography and coronary angiography could not predict the myocardial viability and perfusion as well as PET. Different therapies during the acute stage of the disease did not effectively prevent myocardial damage, despite the absence of coronary arterial abnormalities. The patients who received 400 mg x kg(-1) x day(-1) of intravenous immunoglobulin (IVIG) for 5 days had a significantly lower incidence of PET abnormalities than those who received a single dose of 2000 mg x kg(-1) IVIG (P < 0.05).
B Hwang; R S Liu; L S Chu; P C Lee; J H Lu; L C Meng
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Nuclear medicine communications     Volume:  21     ISSN:  0143-3636     ISO Abbreviation:  Nucl Med Commun     Publication Date:  2000 Jul 
Date Detail:
Created Date:  2001-02-02     Completed Date:  2001-02-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8201017     Medline TA:  Nucl Med Commun     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  631-6     Citation Subset:  IM    
Department of Paediatrics, National Yang-Ming University and Veterans General Hospital, Taipei, Taiwan, Republic of China.
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MeSH Terms
Child, Preschool
Echocardiography, Doppler
Heart / physiopathology,  radionuclide imaging*
Mucocutaneous Lymph Node Syndrome / physiopathology,  radionuclide imaging*,  therapy
Myocardium / metabolism
Nitrogen Radioisotopes / diagnostic use
Quaternary Ammonium Compounds / diagnostic use
Radiopharmaceuticals / diagnostic use
Tomography, Emission-Computed
Reg. No./Substance:
0/Nitrogen Radioisotopes; 0/Quaternary Ammonium Compounds; 0/Radiopharmaceuticals

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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