| Positive correlation between symptoms and circulating motilin, pancreatic polypeptide and gastrin concentrations in functional bowel disorders. | |
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MedLine Citation:
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PMID: 4054704 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Motilin, pancreatic polypeptide and gastrin blood concentrations in response to drinking water have been studied in 40 patients with functional bowel disease and compared with results in two groups of healthy control subjects. Patients with slow transit constipation and idiopathic megacolon showed impaired motilin release. Pancreatic polypeptide release was reduced in patients with slow transit constipation, but increased in those with functional diarrhoea. Gastrin release was impaired in all groups complaining of chronic constipation. Circulating motilin, pancreatic polypeptide and gastrin concentrations appear to bear some relationship to intestinal transit time in patients with functional bowel disorders. |
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Authors:
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D M Preston; T E Adrian; N D Christofides; J E Lennard-Jones; S R Bloom |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Gut Volume: 26 ISSN: 0017-5749 ISO Abbreviation: Gut Publication Date: 1985 Oct |
Date Detail:
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Created Date: 1985-12-04 Completed Date: 1985-12-04 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 2985108R Medline TA: Gut Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 1059-64 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Colonic Diseases, Functional / blood Constipation / blood Diarrhea / blood Drinking Female Gastrins / blood* Humans Intestinal Diseases / blood* Male Megacolon / blood Middle Aged Motilin / blood* Pancreatic Polypeptide / blood* Water / pharmacology |
| Chemical | |
Reg. No./Substance:
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0/Gastrins; 52906-92-0/Motilin; 59763-91-6/Pancreatic Polypeptide; 7732-18-5/Water |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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