| Positive apraclonidine test 36 hours after acute onset of horner syndrome in dorsolateral pontomedullary stroke. | |
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MedLine Citation:
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PMID: 20182200 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 40-year-old man developed a Horner syndrome as part of a dorsolateral medullary brainstem infarction. Thirty-six hours after the onset of the stroke, topical instillation of 0.5% apraclonidine produced reversal of anisocoria. This is the first case in which apraclonidine testing has been applied to a patient with a Horner syndrome caused by a lesion in the first segment of the oculosympathetic pathway and the shortest reported interval between clinical manifestations of the lesion and apraclonidine-induced reversal of anisocoria. A review of all reported cases of apraclonidine testing in Horner syndrome suggests that this is a promising diagnostic adjunct that must be validated in larger studies. |
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Authors:
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Maud Lebas; Julien Seror; Thomas Debroucker |
Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society Volume: 30 ISSN: 1536-5166 ISO Abbreviation: J Neuroophthalmol Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-02-25 Completed Date: 2010-05-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9431308 Medline TA: J Neuroophthalmol Country: United States |
Other Details:
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Languages: eng Pagination: 12-7 Citation Subset: IM |
Affiliation:
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Department of Ophthalmology, H?pital Delafontaine, Saint-Denis, France. maudjacob@gmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic alpha-Agonists
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diagnostic use* Adult Clonidine / analogs & derivatives*, diagnostic use Horner Syndrome / diagnosis*, etiology Humans Magnetic Resonance Angiography / methods Magnetic Resonance Imaging Male Pons / pathology* Stroke / complications, pathology* |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic alpha-Agonists; 4205-90-7/Clonidine; 66711-21-5/apraclonidine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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