| Positive Prolactin Response to Bromocriptine in Two Patients with Cabergoline Resistant Prolactinomas. | |
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MedLine Citation:
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PMID: 21324816 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Objective: To describe a positive prolaction response to bromocriptine treatment in two patients with cabergoline-resistant prolactinomas.Methods: The details of case presentation, evaluation, and clinical course are reviewed in two patients resistant to cabergoline therapy who responded to bromocriptine therapy.Results: Patient 1 was a 45-year-old woman whose prolactin remained elevated at 80 ng/mL (reference range, 2.3-26.7 ng/mL) on 0.5 mg daily of cabergoline, and then decreased to 13 ng/mL on bromocriptine 5 mg daily. Patient 2 was a 15 year-old girl whose prolactin remained elevated at 212 ng/mL on 1 mg three times weekly of cabergoline, and then decreased to 133 ng/mL on bromocriptine 10 mg daily.Conclusion: Although cabergoline is generally preferred to bromocriptine for the treatment of patients with prolactinomas because of its better tolerance profile and greater efficacy, in patients with cabergoline resistant prolactinomas a trial with bromocriptine should be considered as a safe, relatively inexpensive, and well-tolerated alternative. |
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Authors:
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Pallavi Iyer; Mark E Molitch |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-2-16 |
Journal Detail:
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Title: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists Volume: - ISSN: 1934-2403 ISO Abbreviation: - Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-2-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9607439 Medline TA: Endocr Pract Country: - |
Other Details:
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Languages: ENG Pagination: 1-11 Citation Subset: - |
Affiliation:
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Department of Pediatrics, Division of Endocrinology, Diabetes, and Metabolism, University of South Florida, All Children's Hospital, Tampa, FL. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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