Document Detail

Positioning cytokinesis.
MedLine Citation:
PMID:  19299557     Owner:  NLM     Status:  MEDLINE    
Cytokinesis is the terminal step of the cell cycle during which a mother cell divides into daughter cells. Often, the machinery of cytokinesis is positioned in such a way that daughter cells are born roughly equal in size. However, in many specialized cell types or under certain environmental conditions, the cell division machinery is placed at nonmedial positions to produce daughter cells of different sizes and in many cases of different fates. Here we review the different mechanisms that position the division machinery in prokaryotic and eukaryotic cell types. We also describe cytokinesis-positioning mechanisms that are not adequately explained by studies in model organisms and model cell types.
Snezhana Oliferenko; Ting Gang Chew; Mohan K Balasubramanian
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Genes & development     Volume:  23     ISSN:  1549-5477     ISO Abbreviation:  Genes Dev.     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2009-03-20     Completed Date:  2009-05-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8711660     Medline TA:  Genes Dev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  660-74     Citation Subset:  IM    
Temasek Life Sciences Laboratory and the Department of Biological Sciences, National University of Singapore, Singapore, Singapore.
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MeSH Terms
Cell Division / physiology
Cell Shape / physiology*
Cytokinesis / physiology*
Microtubules / physiology*
Mitotic Spindle Apparatus / physiology*

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