Document Detail

Positioning accuracy for lung stereotactic body radiotherapy patients determined by on-treatment cone-beam CT imaging.
MedLine Citation:
PMID:  22665927     Owner:  NLM     Status:  MEDLINE    
Stereotactic body radiotherapy for early stage non-small cell lung cancer is an emerging treatment option in the UK. Since relatively few high-dose ablative fractions are delivered to a small target volume, the consequences of a geometric miss are potentially severe. This paper presents the results of treatment delivery set-up data collected using Elekta Synergy (Elekta, Crawley, UK) cone-beam CT imaging for 17 patients immobilised using the Bodyfix system (Medical Intelligence, Schwabmuenchen, Germany). Images were acquired on the linear accelerator at initial patient treatment set-up, following any position correction adjustments, and post-treatment. These were matched to the localisation CT scan using the Elekta XVI software. In total, 71 fractions were analysed for patient set-up errors. The mean vector error at initial set-up was calculated as 5.3 ± 2.7 mm, which was significantly reduced to 1.4 ± 0.7 mm following image guided correction. Post-treatment the corresponding value was 2.1 ± 1.2 mm. The use of the Bodyfix abdominal compression plate on 5 patients to reduce the range of tumour excursion during respiration produced mean longitudinal set-up corrections of -4.4 ± 4.5 mm compared with -0.7 ± 2.6 mm without compression for the remaining 12 patients. The use of abdominal compression led to a greater variation in set-up errors and a shift in the mean value.
N D Richmond; K E Pilling; C Peedell; D Shakespeare; C P Walker
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The British journal of radiology     Volume:  85     ISSN:  1748-880X     ISO Abbreviation:  Br J Radiol     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-06-05     Completed Date:  2012-08-06     Revised Date:  2013-07-12    
Medline Journal Info:
Nlm Unique ID:  0373125     Medline TA:  Br J Radiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  819-23     Citation Subset:  AIM; IM    
Regional Medical Physics Department, The James Cook University Hospital, Middlesbrough, UK.
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MeSH Terms
Carcinoma, Non-Small-Cell Lung / radiography*,  surgery*
Cone-Beam Computed Tomography*
Lung Neoplasms / radiography*,  surgery*
Patient Positioning / standards*
Radiosurgery / methods*

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