Document Detail

Positional relationship between recurrent intracerebral hemorrhage/lacunar infarction and previously detected microbleeds.
MedLine Citation:
PMID:  20448017     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND PURPOSE: Although MBs, ICH, and LI are secondary to cerebral microangiopathy, it remains unclear whether the location of subsequent ICH/LI corresponds to the previous location of MBs. We performed this study to clarify the positional relationship between recurrent ICH/LI and previously detected MBs.
MATERIALS AND METHODS: We evaluated patients with recurrent ICH/LI who had MBs, as shown on prior T2*-weighted MR imaging. We assessed retrospectively whether the location of recurrent ICH/LI corresponded to that of the prior MB. Patients with ICH were divided into the deep ICH group and the lobar ICH group, and the positional relationship between hematoma and previously detected MBs was evaluated.
RESULTS: A total of 55 patients, including 34 with recurrent ICH and 21 with recurrent LI were evaluated. Although the location of the LI corresponded to prior MBs in only 1 patient (4.8%), the location of ICH corresponded to prior locations of MBs in 21 patients (61.8%) (OR, 32.3; 95% CI, 3.86-270.3; P < .001). Among the patients with ICH, the correspondence ratio was higher in the deep ICH group (19 of 24 patients, 79.2%) than in the lobar ICH group (2 of 10 patients, 20%) (OR, 15.2; 95% CI, 2.42-95.3; P < .002).
CONCLUSIONS: The close positional association between recurrent ICH and prior MBs suggests that MBs represent hemorrhage-prone microangiopathy. In addition, different correspondence ratios between the deep ICH group and the lobar ICH group may be attributable to their different pathogenesis.
Y Sueda; H Naka; T Ohtsuki; T Kono; S Aoki; T Ohshita; E Nomura; S Wakabayashi; T Kohriyama; M Matsumoto
Related Documents :
25483897 - Del nido versus buckberg cardioplegia in adult isolated valve surgery.
15165787 - Gamma knife radiosurgery for trigeminal neuralgia: a study of predictors of success, ef...
18596887 - Single versus multiple fractions of palliative radiotherapy for bone metastases: a rand...
17353327 - Nidal embolization of brain arteriovenous malformations using onyx in 94 patients.
8583067 - Salvage of the failed darrach procedure.
25475807 - Neurological function of the puborectalis muscle in patients with or without soiling af...
Publication Detail:
Type:  Journal Article     Date:  2010-05-06
Journal Detail:
Title:  AJNR. American journal of neuroradiology     Volume:  31     ISSN:  1936-959X     ISO Abbreviation:  AJNR Am J Neuroradiol     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-13     Completed Date:  2011-01-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8003708     Medline TA:  AJNR Am J Neuroradiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1498-503     Citation Subset:  IM    
Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical Science, Hiroshima, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aged, 80 and over
Brain Infarction / pathology*
Cerebral Hemorrhage / pathology*
Cerebrovascular Circulation*
Hematoma / pathology
Magnetic Resonance Imaging*
Microvessels / pathology
Middle Aged
Putamen / blood supply,  pathology
Retrospective Studies
Thalamus / blood supply,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Rituximab (Rituxan).
Next Document:  IgG glycan hydrolysis attenuates ANCA-mediated glomerulonephritis.