Document Detail

Portal vein phlebolithiasis found post-liver transplantation in the native liver of a child with biliary atresia.
MedLine Citation:
PMID:  11260490     Owner:  NLM     Status:  MEDLINE    
Biliary atresia is defined as partial or total obliteration of the extra-hepatic bile ducts. In advanced cases, liver transplantation (LTx) is considered the most appropriate treatment. This report describes a female patient whose biliary atresia and subsequent cirrhosis required LTx at 1 yr of age. Macroscopic inspection of the hilar region of the native liver post-Tx revealed the formation of a pouch in the hepatic duct and a stone in the lumen of the portal vein. X-ray diffraction analysis showed that the stone was composed of cholesteryl cinnamate, gluconic acid phenylhydrazide, Na beta broma-allyl mercaptomethyl penicillinate, and Al2O3 crystals. While the cholesterol component is a known element of gallstones, we attributed the Na beta broma-allyl mercaptomethyl penicillinate to the patient's drug therapy. Our literature search revealed no previous record or crystallographic analysis of portal vein phlebolithiasis. In this report we describe this rare finding.
B Bilezikçi; B Demirhan; H Kiyici; M Haberal
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric transplantation     Volume:  5     ISSN:  1397-3142     ISO Abbreviation:  Pediatr Transplant     Publication Date:  2001 Feb 
Date Detail:
Created Date:  2001-03-30     Completed Date:  2001-05-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9802574     Medline TA:  Pediatr Transplant     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  56-9     Citation Subset:  IM    
Department of Pathology, Baskent University, Ankara, Turkey.
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MeSH Terms
Biliary Atresia / complications*,  pathology,  surgery
Calculi / chemistry,  etiology*
Jaundice / etiology,  surgery
Liver Transplantation*
Portal Vein*
Venous Thrombosis / complications*

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