Document Detail

Portal vein arterialization in hepatobiliary surgery and liver transplantation.
MedLine Citation:
PMID:  17692639     Owner:  NLM     Status:  MEDLINE    
We reviewed the literature reports and our personal experience on partial portal vein arterialization (PPVA) to prevent and treat acute liver failure (ALF) following major hepatobiliary surgery or another etiology. Experimental studies in rats have assessed the efficacy of PPVA in treatment of ALF induced by extended resections in normal or fatty livers or in toxic carbon-tetrachloride damage. The treated groups showed greater survival and faster recovery of liver function. Among 11 clinical cases reported in the literature, PPVA was performed in four cases to prevent and in seven cases to treat ALF. Eight patients survived, showing rapid recovery of liver function and resolution of the clinical condition. This relatively simple procedure has shown itself able to promote liver regeneration. The PPVA procedure has shown itself to be safe and simple as well as to offer a promising approach to the failing liver.
M Tsivian; F Neri; D Prezzi; L Puviani; V Pacile; R Bertelli; G Cavallari; B Mattioli; E Bianchi; G L Piras; M Pariali; B Nardo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Transplantation proceedings     Volume:  39     ISSN:  0041-1345     ISO Abbreviation:  Transplant. Proc.     Publication Date:    2007 Jul-Aug
Date Detail:
Created Date:  2007-08-13     Completed Date:  2007-10-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0243532     Medline TA:  Transplant Proc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1877-8     Citation Subset:  IM    
Center for Applied Biomedical Research (CRBA), S Orsola-Malpighi Hospital, University of Bologna, Italy.
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MeSH Terms
Hepatic Artery*
Liver Circulation*
Liver Failure / prevention & control,  therapy
Liver Regeneration / physiology*
Liver Transplantation / methods*
Portal Vein / surgery*
Postoperative Complications / prevention & control

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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