| Portal thrombosis due to intrahepatic cholangiocarcinoma following successful treatment for hepatocellular carcinoma. | |
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MedLine Citation:
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PMID: 12845999 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 57-year-old man, who had undergone hepatic arterial infusion chemotherapy with right portal occlusion for hepatocellular carcinoma was admitted to our hospital because of severe abdominal pain. Contrast-enhanced computed tomograms revealed that most areas of the liver were not enhanced, a finding suspicious for perfusion disturbance in the liver. Angiography revealed an interrupted right hepatic artery. Arterial portograms revealed complete obstruction of the right portal vein and a small left branch of the portal vein. Despite anticoagulant therapy with urokinase for portal vein thrombosis, the patient died from hepatorenal failure. Autopsy revealed that cholangiocarcinoma occupied almost the entire parenchyma of the right lobe, although the treated hepatocellular carcinoma lesion was completely necrotic. The right hepatic artery was obstructed due to direct invasion of tumor. There were diffuse thrombi in the left portal branches surrounded by tumor infiltrating along Glisson's sheath to the peripheral portion of the left lobe. |
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Authors:
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Takahiro Uenishi; Kazuhiro Hirohashi; Tomoko Haba; Kenichi Wakasa; Shoji Kubo; Taichi Shuto; Hiromu Tanaka; Takatsugu Yamamoto; Shogo Tanaka; Hiroaki Kinoshita |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Hepato-gastroenterology Volume: 50 ISSN: 0172-6390 ISO Abbreviation: Hepatogastroenterology Publication Date: 2003 Jul-Aug |
Date Detail:
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Created Date: 2003-07-08 Completed Date: 2003-10-08 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8007849 Medline TA: Hepatogastroenterology Country: Greece |
Other Details:
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Languages: eng Pagination: 1140-2 Citation Subset: IM |
Affiliation:
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Department of Gastroenterological and Hepato-Biliary-Pancreatic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan. m6877710@msic.med.osaka-cu.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Bile Duct Neoplasms
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complications* Bile Ducts, Intrahepatic* Carcinoma, Hepatocellular / complications, drug therapy Cholangiocarcinoma / complications*, pathology Fatal Outcome Hepatic Artery / pathology Humans Male Middle Aged Neoplasm Invasiveness Neoplasms, Multiple Primary / complications Portal Vein* / pathology Venous Thrombosis / etiology*, pathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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