| Portal hypertensive colopathy and haematochezia in cirrhotic patients: An endoscopic study. | |
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MedLine Citation:
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PMID: 22305498 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BACKGROUND AND STUDY AIMS: In patients with liver cirrhosis, portal hypertensive colopathy (PHC) and anorectal varices (ARVs) are thought to cause lower gastrointestinal (GI) bleeding. In the present work, we studied the diagnostic yield of colonoscopy in cirrhotic patients and haematochezia. PATIENTS AND METHODS: The current study was conducted on 77 consecutive cirrhotic patients who underwent colonoscopy at Mansoura Emergency Hospital, Egypt, between May 2007 and May 2011. Following rapid evaluation and adequate resuscitation, a thorough history was obtained with complete physical examination including digital rectal examination and routine laboratory investigations. Colonoscopic evaluation was performed for the included patients by recording endoscopic abnormalities and obtaining biopsies from lesions. RESULTS: There was no significant difference between the PHC-positive group when compared with the PHC-negative group regarding patients' age, sex, severity of haematochezia, positive family history and the history of intake of non-steroidal anti-inflammatory drugs (NSAIDs). Significant difference was noted regarding the Child-Pugh class (p<0.05), history of splenectomy (p<0.05), prior history of endoscopic sclerotherapy (EST) or endoscopic variceal ligation (EVL) (p<0.05), prior history of upper gut bleeding (p<0.05), the presence of gastric varices (GVs) (p<0.05), presence of portal hypertensive gastropathy (PHG) (p<0.05), presence of haemorrhoids (p<0.05) and rectal varices (<0.05) and therapy with β-blockers (p<0.05). Regarding the laboratory parameters, the platelet count only was markedly reduced in the PHC-positive group (p<0.05). All the PHC-related sources of bleeding (7/32 cases (21.87%)) were successfully managed with argon plasma coagulation. Regarding the laboratory parameters, the platelet count only was markedly reduced in the PHC-positive group (p<0.05). All the PHC-related sources of bleeding (7/32 cases (21.87%)) were successfully managed with argon plasma coagulation. CONCLUSION: Our data revealed that it is not only PHC which is involved in haematochezia in cirrhotic patients despite the significant association. Instead, a high prevalence of inflammatory lesions came on the top of the list. Complete colonoscopy is highly advocated to detect probable proximal neoplastic lesions. |
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Authors:
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Yahia Z Gad; Adel A Zeid |
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Publication Detail:
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Type: Journal Article Date: 2011-12-20 |
Journal Detail:
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Title: Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology Volume: 12 ISSN: 2090-2387 ISO Abbreviation: Arab J Gastroenterol Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2012-02-06 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101298363 Medline TA: Arab J Gastroenterol Country: Egypt |
Other Details:
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Languages: eng Pagination: 184-8 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Arab Journal of Gastroenterology. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Internal Medicine, Hepatogastroenterology Unit, Mansoura Specialized Medical Hospital, Mansoura University, Mansoura, Egypt. |
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