| Portal hypertension in kala-azar. | |
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MedLine Citation:
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PMID: 5045707 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The present study records haemodynamic studies in three patients with kala-azar, a parasitic disease. All the three patients had high intrasplenic pressure, mild to moderate elevation of wedged hepatic vein pressure, and increased or normal estimated hepatic blood flow. Liver histology showed marked proliferation and swelling of Kupffer cells in the sinusoids. One patient was studied serially for nine months following treatment which showed persistent elevation of intrasplenic pressure though wedge pressure and liver blood flow touched normal levels. Liver biopsy was essentially normal at this stage. These findings may have some relevance to the role of different parasitic infections in the pathogenesis of a heterogeneous group of non-cirrhotic portal fibroses. |
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Authors:
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D V Datta; S Saha; S L Grover; S A Singh; R N Chakravarti; P N Chhuttani |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Gut Volume: 13 ISSN: 0017-5749 ISO Abbreviation: Gut Publication Date: 1972 Feb |
Date Detail:
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Created Date: 1972-09-19 Completed Date: 1972-09-19 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 2985108R Medline TA: Gut Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 147-52 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Biopsy Blood Flow Velocity Humans Hypertension, Portal / etiology* Leishmaniasis, Visceral / complications* Liver / pathology Liver Circulation Macrophages Male Mononuclear Phagocyte System Spleen / physiopathology Vascular Resistance Venous Pressure |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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