Document Detail

Portal hemodynamics in chronic liver disease.
MedLine Citation:
PMID:  10319539     Owner:  NLM     Status:  MEDLINE    
Portal hypertension is a result of interplay of numerous static and dynamic forces. Portal hemodynamic characterization involves pressure and flow studies which in turn estimate portal pressure. Hepatic venous pressure gradient is the gold standard for determining portal pressure. Portal hemodynamic measurement has helped to understand the pathogenesis and prognosis of chronic liver disease and to define clinically important hepatic venous pressure gradients. Management strategies for ascites and prevention of variceal hemorrhage have been influenced by hemodynamic studies in animals and humans. The hemodynamics in non-cirrhotic portal fibrosis is ambiguous. The role of portal hemodynamic studies outside clinical trials needs further study.
A Nagral; D Patch; A K Burroughs
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology     Volume:  18     ISSN:  0254-8860     ISO Abbreviation:  Indian J Gastroenterol     Publication Date:    1999 Apr-Jun
Date Detail:
Created Date:  1999-05-28     Completed Date:  1999-05-28     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8409436     Medline TA:  Indian J Gastroenterol     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  78-83     Citation Subset:  IM    
Kasturba Hospital of Infectious Diseases, Bhatia General Hospital, Mumbai.
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MeSH Terms
Chronic Disease
Hypertension, Portal / etiology,  physiopathology*
Liver Diseases / complications*,  physiopathology
Portal System / physiopathology*
Splanchnic Circulation / physiology

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