Document Detail


Portal flow and hepatic function after splenectomy and esophagogastric devascularization.
MedLine Citation:
PMID:  20085039     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We studied 27 patients who had mansonic schistosomiasis and portal hypertension with previous episodes of digestive bleeding from esophageal varices. According to the routine of the Liver and Portal Hypertension Unit of the Faculty of Medical Sciences-Santa Casa de S?o Paulo, these patients underwent surgical treatment that consisted of azygoportal disconnection and splenectomy. The goal of this study was to analyze the developmental profile of portal flow and hepatic function using Doppler ultrasound and the Child-Turcotte-Pugh criteria, respectively, in the pre- and postoperatory stages, in a 3-year period. The results showed a significant 27% reduction of the portal blood flow in the recent postoperatory period and up to 37% in the first to the second year after surgery, remaining stable after this period. We observed that all patients presented with good hepatic functional reserve in the preoperatory period, with no hepatic alteration in the postoperatory period. We conclude that, despite the reduction of portal flow in response to surgery, there was no deterioration of hepatic function.
Authors:
Darcy L M Carvalho; Armando Capua; Pedro L S Leme
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International surgery     Volume:  93     ISSN:  0020-8868     ISO Abbreviation:  Int Surg     Publication Date:    2008 Nov-Dec
Date Detail:
Created Date:  2010-01-20     Completed Date:  2010-02-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0043524     Medline TA:  Int Surg     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  314-20     Citation Subset:  IM    
Affiliation:
Surgery Department, Santa Casa S?o Paulo Faculty of Medical Sciences, S?o Paulo, Brazil. lauga@terra.com.br
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MeSH Terms
Descriptor/Qualifier:
Blood Flow Velocity
Hepatic Artery / physiopathology,  ultrasonography
Hepatic Veins / physiopathology,  ultrasonography
Humans
Hypertension, Portal / complications
Liver / physiopathology*
Portal System / physiopathology*,  surgery*,  ultrasonography
Postoperative Period
Schistosomiasis mansoni / complications,  physiopathology*,  surgery*,  ultrasonography
Splenectomy*
Splenic Vein / physiopathology,  ultrasonography
Ultrasonography, Doppler

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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