| Portable device for quantifying parkinsonian wrist rigidity. | |
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MedLine Citation:
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PMID: 7908119 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The need for objectivity in the assessment of parkinsonism prompted the development of a portable transducer capable of quantifying muscular rigidity. This paper describes the development and use of a device for measuring wrist rigidity and reports the preliminary findings from 25 normal healthy controls and 29 patients, many of whom were undergoing antiparkinsonian treatment to alleviate rigidity or antipsychotic treatment, which produced parkinsonian rigidity. An objective rigidity score, representing the degree to which motor activity increases muscular stiffness in the wrist, correlates highly with clinical ratings of parkinsonian rigidity and demonstrates 89% specificity and 82% sensitivity. Unlike previous techniques for quantifying rigidity, this transducer offers greater portability and apparent face validity. |
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Authors:
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M P Caligiuri |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Movement disorders : official journal of the Movement Disorder Society Volume: 9 ISSN: 0885-3185 ISO Abbreviation: Mov. Disord. Publication Date: 1994 Jan |
Date Detail:
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Created Date: 1994-04-25 Completed Date: 1994-04-25 Revised Date: 2009-10-06 |
Medline Journal Info:
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Nlm Unique ID: 8610688 Medline TA: Mov Disord Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 57-63 Citation Subset: IM |
Affiliation:
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Department of Psychiatry, University of California, San Diego. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Antiparkinson Agents / adverse effects, therapeutic use Antipsychotic Agents / administration & dosage, adverse effects* Carbidopa / adverse effects, therapeutic use Drug Combinations Dyskinesia, Drug-Induced / diagnosis*, drug therapy, physiopathology Female Humans Levodopa / adverse effects, therapeutic use Male Middle Aged Muscle Rigidity / diagnosis*, drug therapy, physiopathology Muscle Tonus / drug effects, physiology* Neurologic Examination / drug effects, instrumentation* Parkinson Disease / diagnosis*, drug therapy, physiopathology Parkinson Disease, Secondary / chemically induced*, diagnosis, physiopathology Psychotic Disorders / drug therapy Risk Factors Transducers |
| Grant Support | |
ID/Acronym/Agency:
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R29MH45959/MH/NIMH NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Antiparkinson Agents; 0/Antipsychotic Agents; 0/Drug Combinations; 0/Levodopa; 0/carbidopa, levodopa drug combination; 38821-49-7/Carbidopa |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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