| Porous hydroxyapatite reinforced with collagen protein. | |
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MedLine Citation:
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PMID: 8922236 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Porous hydroxyapatite (HAP) with certain porosity and pore size was prepared, and incorporated with bovine collagen protein. The composition and structure of the HAP was confirmed by X-Ray Diffraction (XRD) and ICP. Scanning Electron Microscopy (SEM), mechanical tests and in vitro degradation were performed. Collagen protein with low antigenicity was obtained from bovine tendon by enzyme digestion, and was then forced to fill in the HAP matrix to form composites. Scanning Electron Microscopy (SEM), Mechanical tests and in vitro degradation were performed. The test results show that first, HAP thus made has specific pore size and directions; second, mechanical properties of the composites have been markedly improved; third, the in vitro degradation rate of the composite is almost the same as and mainly controlled by the degradation rate of collagen. |
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Authors:
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Q Q Zhang; L Ren; C Wang; L R Liu; X J Wen; Y H Liu; X D Zhang |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Artificial cells, blood substitutes, and immobilization biotechnology Volume: 24 ISSN: 1073-1199 ISO Abbreviation: Artif Cells Blood Substit Immobil Biotechnol Publication Date: 1996 Nov |
Date Detail:
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Created Date: 1997-03-04 Completed Date: 1997-03-04 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9431307 Medline TA: Artif Cells Blood Substit Immobil Biotechnol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 693-702 Citation Subset: IM |
Affiliation:
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Department of Biomaterials, Chinese Academy of Medical Sciences, Tianjin, P.R. China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Biomechanics Biomedical Engineering Bone Substitutes / chemistry*, metabolism Cattle Ceramics / chemistry*, metabolism Collagen / chemistry*, metabolism Durapatite / chemistry*, metabolism |
| Chemical | |
Reg. No./Substance:
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0/Bone Substitutes; 0/Ceramics; 1306-06-5/Durapatite; 9007-34-5/Collagen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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