Document Detail

Porencephaly and transverse limb defects following severe maternal trauma in early pregnancy.
MedLine Citation:
PMID:  7735509     Owner:  NLM     Status:  MEDLINE    
A 13 year old boy with mental retardation, hemiatrophy and left hemiplegia, right hemifacial microsomia and transverse digital amputations is reported. He is moderately mentally retarded, experiences grand mal seizures and has evidence of a porencephalic cyst in the right frontotemporal region on CT scan. At 52 days post conception his mother was involved in a road traffic accident and suffered extensive bruising of the abdomen and concussion. It is suggested that the patient's congenital anomalies are a consequence of hypoxia and thrombo-embolic events sustained during early pregnancy.
D L Viljoen
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical dysmorphology     Volume:  4     ISSN:  0962-8827     ISO Abbreviation:  Clin. Dysmorphol.     Publication Date:  1995 Jan 
Date Detail:
Created Date:  1995-06-07     Completed Date:  1995-06-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9207893     Medline TA:  Clin Dysmorphol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  75-8     Citation Subset:  IM    
Department of Human Genetics, University of Cape Town Medical School, Observatory, South Africa.
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MeSH Terms
Abnormalities, Multiple / etiology*
Accidents, Traffic
Brain / abnormalities*
Facial Asymmetry / etiology
Fetal Hypoxia / etiology
Gestational Age
Hemiplegia / etiology
Limb Deformities, Congenital*
Mental Retardation / etiology
Pregnancy Complications*
Thromboembolism / etiology
Wounds and Injuries / complications*

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