| Porcine xenograft biosynthetic wound dressings for the management of postoperative Mohs wounds. | |
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MedLine Citation:
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PMID: 21971266 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Cadaveric allografts and a large variety of other biologic dressings have been reported as being useful for the postoperative management of Mohs micrographic surgery (MMS) wounds. Although the use of porcine xenografts for the immediate postoperative management of these wounds is known, their use has not been detailed in the dermatology literature. A case series of 15 consecutive Mohs micrographic surgery patients (mean age = 74.9 years, range = 49 to 89 years) with wounds initially managed with porcine xenografts is described. Porcine xenografts were useful in a variety of clinical settings following MMS. These included: 1. wound management when tumor margins were indeterminate pending additional dermatopathology studies and 2. wound management when there are issues such as through and through nasal defects involving the mucosa, large wound depth, exposed cartilage and or bone, or patient medical comorbidities that delay or prevent plans for immediate wound reconstruction. Future controlled studies of biologic dressings are needed to determine which options are best for micrographic surgery wounds. Comparisons should also include the traditional option of second intention healing without biologic dressings. |
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Authors:
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David W Raimer; Ashley R Group; Matthew S Petitt; Neda Nosrati; Mika L Yamazaki; Nathan A Davis; Brent C Kelly; Bernard R Gibson; Richard D Montilla; Richard F Wagner |
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Publication Detail:
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Type: Journal Article Date: 2011-09-15 |
Journal Detail:
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Title: Dermatology online journal Volume: 17 ISSN: 1087-2108 ISO Abbreviation: Dermatol. Online J. Publication Date: 2011 |
Date Detail:
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Created Date: 2011-10-05 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9610776 Medline TA: Dermatol Online J Country: United States |
Other Details:
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Languages: eng Pagination: 1 Citation Subset: IM |
Affiliation:
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The University of Texas Medical Branch, Galveston, Texas. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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