Document Detail


Porcine follicular fluid treatment at proestrus diminishes the serum progesterone level of rats in early pregnancy.
MedLine Citation:
PMID:  3993394     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Proestrous rats were treated with porcine follicular fluid (pFF) or porcine serum (pS) extract, afterwards they were put with males together. Next morning, the sperm positive females were considered as day 1 pregnant animals. On days 2, 8 and 14 of pregnancy serum progesterone level was determined by RIA. On days 2 and 8 of pregnancy serum progesterone level of pFF treated animals was significantly lower than that of pS treated ones, but it was not different from the controls on day 14 of pregnancy. The decreased progesterone level indicates that there are biologically active endogenous substances in the pFF (presumably inhibin or granulosa cell luteinization inhibitor) which may responsible for some forms of corpus luteum insufficiency and for some unexplained infertility cases.
Authors:
J Guoth; B Varga
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta physiologica Hungarica     Volume:  65     ISSN:  0231-424X     ISO Abbreviation:  Acta Physiol Hung     Publication Date:  1985  
Date Detail:
Created Date:  1985-06-07     Completed Date:  1985-06-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8309201     Medline TA:  Acta Physiol Hung     Country:  HUNGARY    
Other Details:
Languages:  eng     Pagination:  53-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Biological Products / pharmacology*
Body Fluids
Estrus*
Female
Organ Size / drug effects
Ovarian Follicle / physiology*
Ovary / anatomy & histology
Pregnancy
Proestrus*
Progesterone / blood*
Rats
Time Factors
Chemical
Reg. No./Substance:
0/Biological Products; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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