Document Detail


Population versus customized fetal growth norms and adverse outcomes in an intrapartum cohort.
MedLine Citation:
PMID:  22893556     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To compare population versus customized fetal growth norms in identifying neonates at risk for adverse outcomes (APO) associated with small for gestational age (SGA).
STUDY DESIGN: Secondary analysis of an intrapartum fetal pulse oximetry trial in nulliparous women at term. Birth weight percentiles were calculated using ethnicity- and gender-specific population norms and customized norms (Gardosi).
RESULTS: Of the studied neonates, 508 (9.9%) and 584 (11.3%) were SGA by population (SGApop) and customized (SGAcust) norms, respectively. SGApop infants were significantly associated with a composite adverse neonatal outcome, neonatal intensive care admission, low fetal oxygen saturation, and reduced risk of cesarean delivery; both SGApop and SGAcust infants were associated with a 5-minute Apgar score < 4. The ability of customized and population birth weight percentiles in predicting APO was poor (12 of 14 APOs had area under the curve of <0.6).
CONCLUSION: In this intrapartum cohort, neither customized nor normalized population norms adequately identified neonates at risk of APO related to SGA.
Authors:
Maged M Costantine; Yinglei Lai; Steven L Bloom; Catherine Y Spong; Michael W Varner; Dwight J Rouse; Susan M Ramin; Steve N Caritis; Alan M Peaceman; Yoram Sorokin; Anthony Sciscione; Brian M Mercer; John M Thorp; Fergal D Malone; Margaret Harper; Jay D Iams;
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Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural     Date:  2012-08-14
Journal Detail:
Title:  American journal of perinatology     Volume:  30     ISSN:  1098-8785     ISO Abbreviation:  Am J Perinatol     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-04-08     Completed Date:  2013-10-17     Revised Date:  2014-04-02    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  335-41     Citation Subset:  IM    
Copyright Information:
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
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MeSH Terms
Descriptor/Qualifier:
Apgar Score*
Birth Weight
Confidence Intervals
Female
Fetal Development / physiology
Fetal Growth Retardation / physiopathology*
Gestational Age
Humans
Infant, Newborn
Infant, Small for Gestational Age*
Intensive Care Units, Neonatal
Male
Oximetry / methods
Pregnancy
Pregnancy Complications / physiopathology*
Pregnancy Outcome*
Prenatal Diagnosis / methods
ROC Curve
Reference Values
Grant Support
ID/Acronym/Agency:
HD21410/HD/NICHD NIH HHS; HD27860/HD/NICHD NIH HHS; HD27869/HD/NICHD NIH HHS; HD27915/HD/NICHD NIH HHS; HD27917/HD/NICHD NIH HHS; HD34116/HD/NICHD NIH HHS; HD34136/HD/NICHD NIH HHS; HD34208/HD/NICHD NIH HHS; HD36801/HD/NICHD NIH HHS; HD40485/HD/NICHD NIH HHS; HD40500/HD/NICHD NIH HHS; HD40512/HD/NICHD NIH HHS; HD40544/HD/NICHD NIH HHS; HD40545/HD/NICHD NIH HHS; HD40560/HD/NICHD NIH HHS; U10 HD053097/HD/NICHD NIH HHS; UL1 RR024989/RR/NCRR NIH HHS
Investigator
Investigator/Affiliation:
A Northen / ; K Bailey / ; J Grant / ; S Tate / ; T Hill-Webb / ; M Carpenter / ; J Tillinghast / ; D Allard / ; P Breault / ; N Connolly / ; J Silva / ; C Milluzzi / ; C Heggie / ; H Ehrenberg / ; B Stetzer / ; V Pemberton / ; S Bousleiman / ; H Husami / ; V Carmona / ; S South / ; M Talucci / ; M Pollock / ; M Sherman / ; C Tocci / ; E Selzer / ; S Brody / ; J Granados / ; K Clark / ; J Mitchell / ; K Dorman / ; G Mallett / ; N Cengic / ; M Huntley / ; T Triplett / ; F Johnson / ; S Fyffe / ; M Landon / ; M Cotroneo / ; M Luce / ; H Birkland / ; M Bickus / ; L Creswell-Hartman / ; M Day / ; F Ortiz / ; B Figueroa / ; S Shaunfield / ; M Messer / ; K Leveno / ; J Gold / ; L Moseley / ; K Anderson / ; B Oshiro / ; F Porter / ; K Jolley / ; A Guzman / ; M Swain / ; J Chilton / ; C Leftwich / ; W Davido / ; K Johnson / ; G Norman / ; B Steffy / ; C Sudz / ; S Blackwell / ; E Thom / ; S Weiner / ; A Swanson / ; F Galbis-Reig / ; L Leuchtenburg / ; S Tolivaisa / ; K Howell / ; G Anderson /
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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