Document Detail

A population-based study of visual inspection with acetic acid (VIA) for cervical screening in rural Nigeria.
MedLine Citation:
PMID:  23354369     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Cervical cancer is the most common gynecological cancer in developing countries. Visual inspection with acetic acid (VIA) was introduced to screen for cervical premalignant lesions in developing countries owing to the inability of many countries to implement high-quality cytologic services. We sought to compare VIA performance among different health workers in Nigeria.
METHODS: In a population-based project, 7 health workers who had been screening women with VIA for approximately 2 years at local government health centers in rural Nigeria were retrained in a 2-week program using the International Agency for Research on Cancer training manual. Women from a rural village who had never had cervical cancer screening were recruited into the study. Each woman had cervical cancer screening by VIA, liquid-based cytologic test, and oncogenic human papillomavirus (HPV) DNA test.
RESULTS: Despite similar participant characteristics, across all age groups, providers had wide ranges of VIA results; 0% to 21% suspect cancer and 0% to 25% were VIA positive. Visual inspection with acetic acid was insensitive compared to a combination of cytologic and HPV tests.
CONCLUSION: In our study, VIA was not reproducible, nor was it sensitive compared to cytologic and HPV tests.
Kayode Olusegun Ajenifuja; Julia C Gage; Akinfolarin C Adepiti; Nicolas Wentzensen; Claire Eklund; Mary Reilly; Martha Hutchinson; Robert D Burk; Mark Schiffman
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society     Volume:  23     ISSN:  1525-1438     ISO Abbreviation:  Int. J. Gynecol. Cancer     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-22     Completed Date:  2013-08-15     Revised Date:  2014-03-06    
Medline Journal Info:
Nlm Unique ID:  9111626     Medline TA:  Int J Gynecol Cancer     Country:  United States    
Other Details:
Languages:  eng     Pagination:  507-12     Citation Subset:  IM    
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MeSH Terms
Acetic Acid / diagnostic use*
Adenocarcinoma / diagnosis*,  epidemiology,  virology
Aged, 80 and over
Carcinoma, Squamous Cell / diagnosis*,  epidemiology,  virology
Cervical Intraepithelial Neoplasia / diagnosis*,  epidemiology,  virology
Early Detection of Cancer
Follow-Up Studies
Mass Screening*
Middle Aged
Neoplasm Staging
Nigeria / epidemiology
Papillomaviridae / genetics
Papillomavirus Infections / diagnosis*,  epidemiology,  virology
Risk Factors
Rural Population
Uterine Cervical Neoplasms / diagnosis*,  epidemiology,  virology
Young Adult
Grant Support
R01 CA078527/CA/NCI NIH HHS; U01 CA078527/CA/NCI NIH HHS; ZIA CP010206-01/CP/NCI NIH HHS
Reg. No./Substance:
Q40Q9N063P/Acetic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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