Document Detail

Popular sweetner sucralose as a migraine trigger.
MedLine Citation:
PMID:  16942478     Owner:  NLM     Status:  MEDLINE    
Sucralose (trichlorogalactosucrose, or better known as Splenda) is an artificial sweetener from native sucrose that was approved by the FDA on April 1, 1998 (April Fool's Day). This observation of a potential causal relationship between sucralose and migraines may be important for physicians to remember this can be a possible trigger during dietary history taking. Identifying further triggers for migraine headaches, in this case sucralose, may help alleviate some of the cost burden (through expensive medical therapy or missed work opportunity) as well as provide relief to migraineurs.
Rajendrakumar M Patel; Rakesh Sarma; Edwin Grimsley
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Headache     Volume:  46     ISSN:  0017-8748     ISO Abbreviation:  Headache     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-08-31     Completed Date:  2007-02-13     Revised Date:  2009-02-02    
Medline Journal Info:
Nlm Unique ID:  2985091R     Medline TA:  Headache     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1303-4     Citation Subset:  IM    
Department of Internal Medicine, Mercer University School of Medicine, Macon, GA, USA.
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MeSH Terms
Middle Aged
Migraine Disorders / chemically induced*
Sucrose / adverse effects,  analogs & derivatives*
Sweetening Agents / adverse effects*
Reg. No./Substance:
0/Sweetening Agents; 56038-13-2/trichlorosucrose; 57-50-1/Sucrose
Comment In:
Headache. 2008 Jan;48(1):164-5   [PMID:  18184301 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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