Document Detail

Poor pregnancy outcome and anticardiolipin antibodies.
MedLine Citation:
PMID:  7818777     Owner:  NLM     Status:  MEDLINE    
The present study reports for the first time on the presence of anticardiolipin antibodies (aCL) in a population of 259 women with a history of recurrent abortion, intrauterine death, and/or neonatal death associated with fetal growth restriction, preeclampsia and abruptio placentae. The overall incidence of aCL in this study group was 20.5%, a statistically significant increase in comparison with a control group. The highest positive rate was observed among women who presented both recurrent abortion and intrauterine death (33.3%), the lowest was observed among women with a history of neonatal death. Our findings confirm that aCL are strongly linked with fetal loss. Thus, before planning a subsequent pregnancy, the presence of aCL should be tested in all women with poor pregnancy outcome.
S De Carolis; A Caruso; S Ferrazzani; B Carducci; L De Santis; S Mancuso
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Fetal diagnosis and therapy     Volume:  9     ISSN:  1015-3837     ISO Abbreviation:  Fetal. Diagn. Ther.     Publication Date:    1994 Sep-Oct
Date Detail:
Created Date:  1995-02-16     Completed Date:  1995-02-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9107463     Medline TA:  Fetal Diagn Ther     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  296-9     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Catholic University, Rome, Italy.
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MeSH Terms
Abortion, Habitual / immunology
Antibodies, Anticardiolipin / blood*
Fetal Death / immunology
Fetal Growth Retardation / immunology
Placenta Diseases / immunology
Pre-Eclampsia / immunology
Pregnancy Outcome*
Reg. No./Substance:
0/Antibodies, Anticardiolipin

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