Document Detail


Poor correlation between left and right ventricular ejection fractions in patients with normal ventricular function.
MedLine Citation:
PMID:  19343163     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
BACKGROUND AND OBJECTIVE: Correlation between right and left ventricular ejection fraction (RVEF, LVEF) has been studied in only a small number of patients with a marked decrease in RVEF and LVEF. The goal of the present study was to compare LVEF and RVEF in a large population with low and normal ejection fractions (EFs) measured by blood pool scintigraphy.
METHODS: A series of 152 patients who underwent LVEF measurement for a clinical indication also underwent simultaneous measurement of the RVEF. The correlation between RVEF and LVEF in patients with or without depressed EF was studied using Pearson's regression analysis.
RESULTS: Although RVEF and LVEF were significantly correlated in an S curve mathematical function, the correlation was weak when the entire cohort was considered (r=0.32; P<0.001). However, when patients with lower EF (LVEF and RVEF less than 50%) were considered, the correlation was stronger (r=0.41; P<0.001), and in patients with normal biventricular EF (LVEF and RVEF 50% or greater), the correlation was completely absent (r=0.001; P=0.86). The strongest correlation between RVEF and LVEF occurred in patients with LVEF and RVEF less than 30% (r=0.75, P=0.03).
CONCLUSION: Patients with decreased EF have highest correlation between LVEF and RVEF in comparison with no correlation in patients with normal EF. The cause of this discrepancy is not known.
Authors:
Mohammad Reza Movahed; Norah Milne
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Experimental and clinical cardiology     Volume:  13     ISSN:  1205-6626     ISO Abbreviation:  Exp Clin Cardiol     Publication Date:  2008  
Date Detail:
Created Date:  2009-04-03     Completed Date:  2011-07-14     Revised Date:  2013-05-23    
Medline Journal Info:
Nlm Unique ID:  9715903     Medline TA:  Exp Clin Cardiol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  179-81     Citation Subset:  -    
Affiliation:
Department of Medicine, Section of Cardiology, University of Arizona Sarver Heart Center, Tucson, Arizona, USA.
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