| Pontine myelinolysis following liver transplantation: a report of two cases. | |
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MedLine Citation:
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PMID: 8452628 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two cases of central pontine myelinolysis (CPM) following orthotopic liver transplantation (OLT) are reported. Several months after the onset of this neurological syndrome, the two patients are still alive but with severe neurological sequelae. Some patients undergoing emergency OLT present a high risk of CPM because of pre-existing malnutrition, encephalopathy, and hepatic insufficiency. All of these are associated with an inevitable abrupt rise in sodium serum concentration due to intraoperative compensation of blood losses with high-sodium content blood products. Whenever the renal capacity to excrete sodium is impaired by the surgical procedure, continuous intraoperative venovenous hemofiltration is recommended. |
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Authors:
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S Winnock; G Janvier; F Parmentier; B Duche; P Daverat; C Combe; A Vallet; C Douws; J Carles; J Saric |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Transplant international : official journal of the European Society for Organ Transplantation Volume: 6 ISSN: 0934-0874 ISO Abbreviation: Transpl. Int. Publication Date: 1993 Jan |
Date Detail:
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Created Date: 1993-04-19 Completed Date: 1993-04-19 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8908516 Medline TA: Transpl Int Country: GERMANY |
Other Details:
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Languages: eng Pagination: 26-8 Citation Subset: IM |
Affiliation:
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Department of Anesthesia, Pellegrin University Hospital, Bordeaux, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cyclosporins / adverse effects Demyelinating Diseases / etiology* Female Humans Liver Transplantation / adverse effects* Male Pons* Sodium / blood |
| Chemical | |
Reg. No./Substance:
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0/Cyclosporins; 7440-23-5/Sodium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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