Document Detail

Pomegranate as a functional food and nutraceutical source.
MedLine Citation:
PMID:  22129380     Owner:  NLM     Status:  In-Process    
Pomegranate, a fruit native to the Middle East, has gained widespread popularity as a functional food and nutraceutical source. The health effects of the whole fruit, as well as its juices and extracts, have been studied in relation to a variety of chronic diseases. Promising results against cardiovascular disease, diabetes, and prostate cancer have been reported from human clinical trials. The in vitro antioxidant activity of pomegranate has been attributed to its high polyphenolic content, specifically punicalagins, punicalins, gallagic acid, and ellagic acid. These compounds are metabolized during digestion to ellagic acid and urolithins, suggesting that the bioactive compounds that provide in vivo antioxidant activity may not be the same as those present in the whole food. Anthocyanins and the unique fatty acid profile of the seed oil may also play a role in pomegranate's health effects. A more complete characterization of pomegranate components and their physiological fate may provide mechanistic insight into the potential health benefits observed in clinical trials.
Suzanne D Johanningsmeier; G Keith Harris
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annual review of food science and technology     Volume:  2     ISSN:  1941-1413     ISO Abbreviation:  Annu Rev Food Sci Technol     Publication Date:  2011  
Date Detail:
Created Date:  2011-12-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101561951     Medline TA:  Annu Rev Food Sci Technol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  181-201     Citation Subset:  IM    
USDA-ARS Food Science Research Unit Raleigh, North Carolina 27695; email:
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