| Polyurethane and PTFE membranes for guided bone regeneration: histopathological and ultrastructural evaluation. | |
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MedLine Citation:
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PMID: 19767699 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The purpose of this study was to research a membrane material for use in guided bone regeneration. STUDY DESIGN: In this study, 25 male Wistar rats were used to analyze the biocompatibility and degradation process of biomembranes. The morphological changes in subcutaneous implantations were assessed after 7, 14, 21, 28 and 70 days. The materials were made of polyurethane polymer (AUG) obtained from vegetal oil (Ricinus communis) and polytetrafluoroethylene membrane (PTFE). The surface characteristics of the physical barriers in scanning electronic microscopic (SEM) were also evaluated. RESULTS: In both groups, the initial histological analysis showed moderate inflammatory infiltrate, which was predominantly polymorphonuclear. There was also a presence of edema, which was gradually replaced by granulation tissue, culminating in a fibrous capsule. In the AUG group, some multinucleated giant cells were present in the contact interface, with the space previously occupied by the material. However, membrane degradation was not observed during the period studied. According to the present SEM findings, porosity was not detected in the AUG or PTFE membranes. CONCLUSION: The researched material is biocompatible and the degradation process is extremely slow or may not even occur at all. |
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Authors:
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Adriana-Socorro-Ferreira Monteiro; Lu?s-Guilherme-Scavone Macedo; Nelson-Luiz Macedo; Ivan Balducci |
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Publication Detail:
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Type: Journal Article Date: 2010-03-01 |
Journal Detail:
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Title: Medicina oral, patolog?a oral y cirug?a bucal Volume: 15 ISSN: 1698-6946 ISO Abbreviation: Med Oral Patol Oral Cir Bucal Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-03-01 Completed Date: 2010-06-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101231694 Medline TA: Med Oral Patol Oral Cir Bucal Country: Spain |
Other Details:
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Languages: eng Pagination: e401-6 Citation Subset: D; IM |
Affiliation:
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Department of Diagnosis and Surgery, S?o Jos? dos Campos Dental School, UNESP Avenida Engenheiro Francisco Jos? Longo, 777, Caixa Postal 314, CEP 12245-000, S?o Jos? dos Campos, SP - Brazil. dri.monteiro@fosjc.unesp.br |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bone Regeneration* Bone and Bones / pathology, ultrastructure Guided Tissue Regeneration / methods* Male Membranes, Artificial* Polytetrafluoroethylene* Polyurethanes* Rats Rats, Wistar |
| Chemical | |
Reg. No./Substance:
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0/Membranes, Artificial; 0/Polyurethanes; 9002-84-0/Polytetrafluoroethylene |
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