| Polysilicon wire glucose sensor highly immune to interference. | |
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MedLine Citation:
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PMID: 21030241 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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This study investigated the interference elimination ability of a glucose sensor made of polysilicon wire (PSW) with a surface modified by 3-aminopropyltriethoxysilane mixed with polydimethylsiloxane-treated hydrophobic fumed silica nanoparticles plus ultra-violet illumination (γ-APTES+NPs+UV). Glucose sensing of the PSW sensor in the presence of five common interferences such as ascorbic acid (AA), uric acid (UA), acetaminophen (AP), L-cysteine (Lys), and citric acid (CA) was performed. We found that the disturbance caused by the interferences was low for interference-to-glucose concentration ratios up to 600:1 if the PSW surface is modified with γ-APTES+NPs+UV. The outstanding interference immunity of this PSW glucose sensor is believed to be mainly due to the fact that it is a dry-type sensor and the extremely low leakage of the γ-APTES+NPs membrane which allows the PSW to show three orders of magnitude lower leakage current than with the γ-APTES membrane only. In addition to its excellent interference immunity, the PSW glucose sensor with a line width of 100 nm also exhibits a wide linear detection range, an ultra-high sensitivity, an ultra low detection limit, and it can be reused more than a thousand times without much sensitivity degradation. |
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Authors:
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You-Lin Wu; Po-Yen Hsu; Jing-Jenn Lin |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-10-07 |
Journal Detail:
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Title: Biosensors & bioelectronics Volume: 26 ISSN: 1873-4235 ISO Abbreviation: Biosens Bioelectron Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-01-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9001289 Medline TA: Biosens Bioelectron Country: England |
Other Details:
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Languages: eng Pagination: 2281-6 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier B.V. All rights reserved. |
Affiliation:
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Department of Electrical Engineering, National Chi Nan University, Puli, Nantou, Taiwan, ROC. |
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Descriptor/Qualifier:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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