Document Detail

Polysarcia adiposa: morbid obesity.
MedLine Citation:
PMID:  17721178     Owner:  NLM     Status:  MEDLINE    
From October 1988 to March 2005, there were at least 92 autopsy cases where morbid obesity was present and/or where it was attributed to the cause of death in the coronial district of Auckland, New Zealand, a city with a population of over 1 million people. Obesity has been researched internationally, and much is known about associated comorbidities such as atherosclerotic disease, hypertension, and diabetes, to name a few. However, in the morbidly obese (body mass index>or=40 kg/m2), only 14 of 92 cases were found to have ischemic heart disease due to coronary atherosclerosis as the principal cause of death, and slightly over half (48/92) have some degree (mild, moderate, severe) of coronary atheroma. There is a strong positive correlation between heart weight and body weight. Only 8 livers were normal, all others showing some form of steatosis, venous congestion, and fibrosis/cirrhosis. The mean weights of the heart, lungs, and liver were above the normal reference range in almost all cases. In conclusion, the study did not follow the widely published finding of the positive correlation between morbid obesity and ischemic heart disease in terms of mortality, but the study was consistent with other studies on the organ manifestations of morbid obesity, particularly for the heart, lungs, and liver.
Wing Chuen Chan; Tim Koelmeyer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of forensic medicine and pathology     Volume:  28     ISSN:  0195-7910     ISO Abbreviation:  Am J Forensic Med Pathol     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-08-27     Completed Date:  2007-12-07     Revised Date:  2011-02-02    
Medline Journal Info:
Nlm Unique ID:  8108948     Medline TA:  Am J Forensic Med Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  249-54     Citation Subset:  IM    
University of Auckland, Auckland, New Zealand.
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MeSH Terms
Aged, 80 and over
Cardiomyopathy, Dilated / mortality,  pathology
Cause of Death
Coronary Artery Disease / mortality,  pathology
Edema / pathology
Embolism, Fat / mortality,  pathology
Forensic Pathology
Liver / pathology
Liver Diseases / pathology
Lung / pathology
Middle Aged
Myocardial Ischemia / mortality,  pathology
Myocardium / pathology
New Zealand / epidemiology
Obesity, Morbid / mortality*
Organ Size
Pulmonary Embolism / mortality,  pathology
Respiratory Distress Syndrome, Adult / mortality,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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