Document Detail

Polyploidy in mouse embryos derived from in vivo and in vitro fertilization is dependent on the timing of pregnant mare serum gonadotropin (PMSG) injection.
MedLine Citation:
PMID:  17254578     Owner:  NLM     Status:  MEDLINE    
Nine hundred eighty-seven mouse embryos were cytogenetically analyzed at the two-cell stage to compare aneuploidy rates in embryos derived from both in vivo and in vitro fertilization using two different ovarian stimulation protocols. The rate of polyploidy was significantly (P<.001) elevated in both in vivo fertilized (15.6%) and in vitro fertilized (5.9%) embryos when PMSG injection was given in the afternoon instead of the morning (2.1% and 4.0% respectively).
Douglas T Carrell; Lihua Liu; Greg Christensen
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Publication Detail:
Type:  Journal Article     Date:  2007-01-24
Journal Detail:
Title:  Fertility and sterility     Volume:  87     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-06-04     Completed Date:  2007-09-14     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1470-2     Citation Subset:  IM    
Department of Surgery (Urology), University of Utah School of Medicine, Salt Lake City, Utah, USA. <>
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MeSH Terms
Embryo, Mammalian / drug effects,  physiology*
Fertilization in Vitro
Gonadotropins, Equine / pharmacology*
Models, Animal
Reg. No./Substance:
0/Gonadotropins, Equine

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