| Polyphosphate and stress response in mycobacteria. | |
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MedLine Citation:
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PMID: 17590232 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Polyphosphate (poly P) is present in every living cell. Long considered a 'molecular fossil', its role in cell physiology has been neglected. However, in the last few years it has become clear that poly P plays a role in multiple physiological functions, the best characterized of which is rpoS and recA induction during the Escherichia coli stringent response. Sureka et al. in this issue of Molecular Microbiology investigate the role of poly P in mycobacterial stress response and describe its participation in a novel regulatory pathway involving the two-component system MprAB, the alternative sigma factor sigma(E) and Rel, the enzyme responsible for (p)ppGpp metabolism in mycobacteria. |
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Authors:
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Riccardo Manganelli |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2007-06-21 |
Journal Detail:
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Title: Molecular microbiology Volume: 65 ISSN: 0950-382X ISO Abbreviation: Mol. Microbiol. Publication Date: 2007 Jul |
Date Detail:
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Created Date: 2007-07-16 Completed Date: 2007-10-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8712028 Medline TA: Mol Microbiol Country: England |
Other Details:
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Languages: eng Pagination: 258-60 Citation Subset: IM |
Affiliation:
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Department of Histology, Microbiology and Medical Biotechnologies, University of Padua, Padua, Italy. riccardo.manganelli@unipd.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Mycobacterium
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physiology* Polyphosphates / metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Polyphosphates |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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