Document Detail

Polyphenols isolated from antiradical extracts of Mallotus metcalfianus.
MedLine Citation:
PMID:  19062052     Owner:  NLM     Status:  MEDLINE    
Six flavonoids including two new flavones, luteolin 7-O-(4''-O-(E)-coumaroyl)-beta-glucopyranoside), chrysoeriol-7-O-(4''-O-(E)-coumaroyl)-beta-glucopyranoside) and a mixture of two pairs of diastereoisomeric flavonolignans, (+/-)-hydnocarpin 7-O-(4''-O-(E)-coumaroyl)-beta-glucopyranoside)/(+/-)-hydnocarpin-D 7-O-(4''-O-(E)-coumaroyl)-beta-glucopyranoside) with a 2:1 ratio were isolated from the whole plant of Mallotus metcalfianus Croizat, in addition to 10 known compounds. Their structures were evaluated on the basis of different spectroscopic methods, including extensive 1D and 2D NMR spectroscopy. Some extracts have moderate antimicrobial properties and interesting antiradical (DPPH) activity, as well as some compounds isolated from this species. Tannins were also identified in some active extracts.
Céline Rivière; Van Nguyen Thi Hong; Luc Pieters; Bieke Dejaegher; Yvan Vander Heyden; Minh Chau Van; Joëlle Quetin-Leclercq
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-12-04
Journal Detail:
Title:  Phytochemistry     Volume:  70     ISSN:  0031-9422     ISO Abbreviation:  Phytochemistry     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2009-02-09     Completed Date:  2009-05-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0151434     Medline TA:  Phytochemistry     Country:  United States    
Other Details:
Languages:  eng     Pagination:  86-94     Citation Subset:  IM    
Université Catholique de Louvain, Louvain Drug Research Institute, CHAM Unit, UCL 7230, Avenue E. Mounier 7, B-1200 Brussels, Belgium.
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MeSH Terms
Anti-Bacterial Agents / chemistry,  pharmacology
Bacteria / drug effects
Flavonoids / chemistry*
Mallotus Plant / chemistry*
Molecular Structure
Phenols / chemistry*
Plant Extracts / chemistry*
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Flavonoids; 0/Phenols; 0/Plant Extracts; 0/polyphenols

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