| Polyphenols excreted in urine as biomarkers of total polyphenol intake. | |
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MedLine Citation:
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PMID: 23210653 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Background: Nutritional biomarkers have several advantages in acquiring data for epidemiological and clinical studies over traditional dietary assessment tools, such as food frequency questionnaires. While food frequency questionnaires constitute a subjective methodology, biomarkers can provide a less biased and more accurate measure of specific nutritional intake. A precise estimation of polyphenol consumption requires blood or urine sample biomarkers, although their association is usually highly complex. Results: This article reviews recent research on urinary polyphenols as potential biomarkers of polyphenol intake, focusing on clinical and epidemiological studies. We also report a potentially useful methodology to assess total polyphenols in urine samples, which allows a rapid, simultaneous determination of total phenols in a large number of samples. Conclusion: This methodology can be applied in studies evaluating the utility of urinary polyphenols as markers of polyphenol intake, bioavailability and accumulation in the body. |
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Authors:
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Alexander Medina-Remón; Anna Tresserra-Rimbau; Sara Arranz; Ramón Estruch; Rosa M Lamuela-Raventos |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Bioanalysis Volume: 4 ISSN: 1757-6199 ISO Abbreviation: Bioanalysis Publication Date: 2012 Nov |
Date Detail:
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Created Date: 2012-12-05 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101512484 Medline TA: Bioanalysis Country: England |
Other Details:
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Languages: eng Pagination: 2705-13 Citation Subset: IM |
Affiliation:
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Nutrition & Food Science Department, XaRTA, Instituto de Investigaciónen Nutrición y Seguridad Alimentaria, Pharmacy School, University of Barcelona, Barcelona, Spain. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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