| Polyphenolics and fat absorption. | |
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MedLine Citation:
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PMID: 14970839 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To elucidate whether the acute consumption of red wine polyphenolic compounds regulates lipid and lipoprotein metabolism in dyslipidemic postmenopausal women. DESIGN: Eight dyslipidemic postmenopausal women each consumed a mixed meal accompanied by either water, dealcoholized red wine or alcoholic red wine on three separate visits, in a random order, 2 weeks apart. One fasting and six hourly postmeal blood samples were taken and analyzed for plasma apolipoprotein B48 (apoB48; specific marker of chylomicrons (CM) and their remnants (CMR)); total-, LDL- and HDL-cholesterol; triglycerides (TAG); insulin and glucose at each time point. RESULTS: There was a decrease in postprandial apoB48 levels after alcoholic and nonalcoholic red wine consumption compared to water. CONCLUSION: Red wine attenuates postprandial CM and CMR levels in plasma, possibly by delaying the absorption of dietary fat, as suggested by a decrease in plasma apoB48 levels. The reduction of postprandial lipoproteins in circulation after red wine consumption may partly explain the low cardiovascular mortality rates among the French. |
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Authors:
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S Pal; M Naissides; J Mamo |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity Volume: 28 ISSN: 0307-0565 ISO Abbreviation: Int. J. Obes. Relat. Metab. Disord. Publication Date: 2004 Feb |
Date Detail:
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Created Date: 2004-02-18 Completed Date: 2004-04-12 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9313169 Medline TA: Int J Obes Relat Metab Disord Country: England |
Other Details:
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Languages: eng Pagination: 324-6 Citation Subset: IM |
Affiliation:
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Department of Nutrition, Dietetics and Food Sciences, Curtin University, Perth Western Australia, Australia. s.pal@curtin.edu.au |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Apolipoprotein B-48 Apolipoproteins B / blood Female Flavonoids / pharmacology* Humans Hyperlipidemias / blood* Intestinal Absorption / drug effects Lipids / blood* Phenols / pharmacology* Postmenopause / blood Postprandial Period / physiology Wine / analysis* |
| Chemical | |
Reg. No./Substance:
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0/Apolipoprotein B-48; 0/Apolipoproteins B; 0/Flavonoids; 0/Lipids; 0/Phenols; 0/polyphenols |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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