Document Detail


Polyphenolic acids from mint (the aerial of Mentha haplocalyx Briq.) with DPPH radical scavenging activity.
MedLine Citation:
PMID:  20546395     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Vegetables of mint (the aerial part of Mentha haplocalyx) contain a significant amount of polyphenols with many health benefits. The crude aqueous acetone extract exhibited high antioxidant activity (IC(50)= 45.67 mug/mL) in 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay. The activity-guided separation of chlorophyll removal fraction on column chromatography afforded 8 polyphenolic acids, including a new compound, cis-salvianolic acid J (1), and 7 known compounds, salvianolic acid J (2), lithospermic acid (3), rosmarinic acid (4), lithospermic acid B (5), magnesium lithospermate B (6), sodium lithospermate B (7), and danshensu (8), respectively. Their structural elucidations of all the compounds were based on extensive spectroscopic methods, including HRESIMS and 2D NMR experiments (HSQC, HMBC, and ROESY) and by comparison with reference values. Compounds 2, 3, and 5 to 8 were isolated from Mentha genus for the 1st time. The DPPH radical scavenging activities of all the isolated compounds were evaluated.
Authors:
G-M She; C Xu; B Liu; R-B Shi
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of food science     Volume:  75     ISSN:  1750-3841     ISO Abbreviation:  J. Food Sci.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-06-15     Completed Date:  2010-10-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0014052     Medline TA:  J Food Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  C359-62     Citation Subset:  IM    
Affiliation:
School of Chinese Pharmacy, Beijing Univ. of Chinese Medicine, Beijing 100102, China.
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MeSH Terms
Descriptor/Qualifier:
Antioxidants / analysis,  chemistry,  isolation & purification
Biphenyl Compounds / chemistry
Drugs, Chinese Herbal
Flavonoids / analysis,  chemistry*,  isolation & purification
Free Radical Scavengers / analysis,  chemistry*
Hydroxybenzoic Acids / analysis,  chemistry*,  isolation & purification
Magnetic Resonance Spectroscopy
Mentha / chemistry*
Optical Rotation
Phenols / analysis,  chemistry*,  isolation & purification
Picrates / chemistry
Plant Components, Aerial / chemistry*
Plant Extracts / chemistry*
Spectrometry, Mass, Electrospray Ionization
Spectrophotometry, Ultraviolet
Chemical
Reg. No./Substance:
0/Antioxidants; 0/Biphenyl Compounds; 0/Drugs, Chinese Herbal; 0/Flavonoids; 0/Free Radical Scavengers; 0/Hydroxybenzoic Acids; 0/Phenols; 0/Picrates; 0/Plant Extracts; 0/polyphenols; 1898-66-4/2,2-diphenyl-1-picrylhydrazyl; 29656-58-4/phenolic acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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