| Polymyxin-direct hemoperfusion for sepsis-induced multiple organ failure. | |
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MedLine Citation:
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PMID: 20486188 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report a case of multiple organ failure caused by the Bacillus cereus infection during acute lymphoblastic leukemia therapy, who was treated successfully. A 15-year-old male developed (B. cereus) sepsis on the 19th day after chemotherapy initiation. Polymyxin-direct hemoperfusion for septic shock was started, followed by continuous hemodiafiltration. His condition improved after starting the hemoperfusion. At the onset of sepsis, elevated levels of serum inflammatory cytokines, anti-inflammatory cytokines, and plasminogen-activator inhibitor complex-1 were observed. Serum levels of these cytokines and bioactive substances decreased after blood purification therapy, which correlated with the improvement of clinical symptoms. |
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Authors:
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Koichi Hirabayashi; Masaaki Shiohara; Shoji Saito; Miyuki Tanaka; Ryu Yanagisawa; Goro Tsuruta; Tetsuhiro Fukuyama; Yoshihiko Hidaka; Yozo Nakazawa; Takashi Shimizu; Kazuo Sakashita; Kenichi Koike |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pediatric blood & cancer Volume: 55 ISSN: 1545-5017 ISO Abbreviation: Pediatr Blood Cancer Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-05-20 Completed Date: 2010-06-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101186624 Medline TA: Pediatr Blood Cancer Country: United States |
Other Details:
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Languages: eng Pagination: 202-5 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan. k-hira@naganoch.gr.jp |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Bacillus cereus / isolation & purification Cytokines / blood Hemodiafiltration / methods* Humans Male Multiple Organ Failure / etiology*, therapy* Plasminogen Activator Inhibitor 1 / blood Polymyxins / administration & dosage* Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy* Sepsis / complications*, therapy* |
| Chemical | |
Reg. No./Substance:
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0/Cytokines; 0/Plasminogen Activator Inhibitor 1; 0/Polymyxins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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