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Polymyalgia rheumatica is associated with extensor tendon tenosynovitis but not with synovitis of the hands: a magnetic resonance imaging study.
MedLine Citation:
PMID:  21071481     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Objectives. To study with MRI the hands of consecutive PMR patients, who were not selected on the basis of peripheral arthritis, with a correlation to clinical and laboratory findings. Methods. Twenty-six hands of 15 PMR patients and 26 hands of 13 healthy controls were studied by extremity-dedicated MRI for the presence of synovitis, tenosynovitis, soft-tissue oedema, bone marrow oedema and erosions. Results. Sixteen (61.6%) of the 26 PMR hands and 4 (15.4%) of the 26 control hands showed tenosynovitis (P = 0.001). Extensor tendon tenosynovitis was seen in 9 (34.6%) of the 26 PMR hands, but in only 1 (3.8%) control hand (P = 0.002) and flexor tenosynovitis was seen in 12 (46.1%) of the 26 PMR hands and in 4 (15.4%) of the 26 control hands (P = 0.03). All other features were similar in the two groups. Conclusions. Our data support the view that tenosynovitis, especially of the extensor tendons, is a frequent event in PMR, unrelated to clinical involvement of the hand. This finding is in agreement with the concept of PMR as a disease of extra-articular structures.
Authors:
Marco A Cimmino; Massimiliano Parodi; Giuseppe Zampogna; Francesca Barbieri; Giacomo Garlaschi
Publication Detail:
Type:  Journal Article     Date:  2010-11-11
Journal Detail:
Title:  Rheumatology (Oxford, England)     Volume:  50     ISSN:  1462-0332     ISO Abbreviation:  Rheumatology (Oxford)     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883501     Medline TA:  Rheumatology (Oxford)     Country:  England    
Other Details:
Languages:  eng     Pagination:  494-9     Citation Subset:  AIM; IM    
Affiliation:
Dipartimento di Medicina Interna e Specialità Mediche, Clinica Reumatologica, Viale Benedetto XV 6, 16132 Genova, Italy. cimmino@unige.it.
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