Document Detail


Polymicrogyria in monozygous twins and an elder sibling.
MedLine Citation:
PMID:  12828405     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Monozygous twin births have been associated with brain lesions such as hydranencephaly, multicystic encephalomalacia, and porencephaly. Prenatal circulatory injury has been considered to be the cause. Polymicrogyria is rare but has been reported in autopsied cases. The sibship in this case report, comprising monozygotic male twins and their elder sister from the same non-consanguineous parents, all had global developmental delay. Brain MRI showed polymicrogyria. We suggest that, apart from circulatory compromise, genetic etiology must be implicated as the cause of polymicrogyria.
Authors:
Po-Cheng Hung; Huei-Shyong Wang
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Developmental medicine and child neurology     Volume:  45     ISSN:  0012-1622     ISO Abbreviation:  Dev Med Child Neurol     Publication Date:  2003 Jul 
Date Detail:
Created Date:  2003-06-27     Completed Date:  2003-07-17     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0006761     Medline TA:  Dev Med Child Neurol     Country:  England    
Other Details:
Languages:  eng     Pagination:  494-6     Citation Subset:  IM    
Affiliation:
Division of Pediatric Neurology, Chang Gung Children's Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan. hongfh@ms14.hinet.net
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MeSH Terms
Descriptor/Qualifier:
Brain / abnormalities*
Cerebral Cortex / abnormalities
Diseases in Twins / diagnosis*,  genetics
Family Health
Female
Humans
Infant, Newborn
Magnetic Resonance Imaging
Male
Siblings*
Twins, Monozygotic* / genetics

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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