| Polyhedral microcalcifications at mammography: histologic correlation with calcium oxalate. | |
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MedLine Citation:
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PMID: 8430173 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pathologists have associated calcium oxalate dihydrate (weddellite) in breast biopsy specimens with benign or borderline lesions and rarely with malignancy. These microcalcifications may have a polyhedral shape in histologic specimens owing to their crystalline structure. A retrospective radiologic-histologic correlation study was performed on 300 clusters of microcalcifications to determine if microcalcifications with a polyhedral shape could be found at mammography. In 19 cases (6.3%), polyhedral microcalcifications (PMs) were detected by two radiologists. In 12 of these 19 cases, weddellite crystals were found in the histologic specimen under polarized light; in seven cases, no calcification was found. Although rare, PMs can be found at mammography by radiologists aware of their existence. They are due to weddellite crystals and in this series were associated with benign disease in 89% of cases. Prospective studies are required to determine the frequency of PMs on screening mammograms and to evaluate their negative predictive value. |
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Authors:
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C Frouge; M Meunier; J M Guinebretière; R Gilles; D Vanel; G Contesso; R Di Paola; M Bléry |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Radiology Volume: 186 ISSN: 0033-8419 ISO Abbreviation: Radiology Publication Date: 1993 Mar |
Date Detail:
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Created Date: 1993-03-11 Completed Date: 1993-03-11 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 681-4 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology, Hôpital de Bicêtre, Kremlin Bicêtre, France. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Breast
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chemistry,
pathology* Breast Diseases / epidemiology, metabolism, radiography* Breast Neoplasms / chemistry, epidemiology, radiography* Calcinosis / epidemiology, metabolism, radiography* Calcium Oxalate / analysis* Female Humans Mammography* Middle Aged Retrospective Studies |
| Chemical | |
Reg. No./Substance:
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25454-23-3/Calcium Oxalate; 7236-42-2/weddellite |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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