| Polyethylene and metal wear particles: characteristics and biological effects. | |
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MedLine Citation:
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PMID: 21267569 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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This paper first presents a brief overview about the mechanism of wear particle formation as well as wear particle characteristics in metal-on-polyethylene and metal-on-metal artificial hip joints. The biological effects of such particles are then described, focusing on the inflammatory response induced by each type of particles as well as on how metal wear products may be the source of a T lymphocyte-mediated specific immune response, early adverse tissue responses, and genotoxicity. Finally, some of the current in vivo models used for the analysis of tissue response to various wear particles are presented. |
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Authors:
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Isabelle Catelas; Markus A Wimmer; Sandra Utzschneider |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-1-26 |
Journal Detail:
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Title: Seminars in immunopathology Volume: - ISSN: 1863-2300 ISO Abbreviation: - Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-1-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101308769 Medline TA: Semin Immunopathol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Mechanical Engineering, Departments of Surgery & Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON, Canada. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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