Document Detail


Poly(ether imide) scaffolds as multifunctional materials for potential applications in regenerative medicine.
MedLine Citation:
PMID:  17026575     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This article gives an overview of scaffolds that can be prepared from poly(ether imide) (PEI). These scaffolds were developed for extracorporeal blood detoxification processes in which specific compounds from blood or plasma are removed selectively. Both the preparation of porous microparticles and the preparation of hollow fibers are described. Commercially available particulate support materials have the disadvantage of a low accessibility of the internal pore system, a poor flow-through behavior and low adsorption specificity. Thus, novel support materials with optimally adapted properties profiles are needed. The second part of this article shows some recently developed highly asymmetric PEI hollow fibers. PEI scaffolds can be considered multifunctional because they combine separation characteristics, biocompatibility, sufficient biostability, and the possibility of creating tailor-made biofunctional surfaces.
Authors:
Karola Lützow; Thomas Weigel; Andreas Lendlein
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Artificial organs     Volume:  30     ISSN:  0160-564X     ISO Abbreviation:  Artif Organs     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-10-09     Completed Date:  2007-01-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7802778     Medline TA:  Artif Organs     Country:  United States    
Other Details:
Languages:  eng     Pagination:  764-9     Citation Subset:  IM    
Affiliation:
GKSS Research Center GmbH, Institute of Polymer Research, Teltow, Germany.
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MeSH Terms
Descriptor/Qualifier:
Biocompatible Materials
Ethers / chemistry*
Imides / chemistry*
Materials Testing
Microscopy, Electron, Scanning
Particle Size
Porosity
Regenerative Medicine*
Sorption Detoxification / instrumentation*
Tissue Engineering / instrumentation*
Chemical
Reg. No./Substance:
0/Biocompatible Materials; 0/Ethers; 0/Imides

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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